Brooke is a disabled/Crip artist, academic and expressive arts practitioner. She has made artwork with youth, disability communities, communities in conflict and professionally through collective creation and as a solo performance/theatre artist. She has worked in a producing/administrative capacity with: Edmonton Fringe Theatre, Theatre Yes, Ground Zero Productions, Workshop West Playwrights Theatre, Azimuth Theatre, CRIPSiE, Jumblies Theatre (Toronto). She has also performed with mindhive collective (Dwelling, Held, A Wake, s/kin), Edmonton Actors Theatre (Faerie Queen, Burning Bluebeard), Moon At Midnight (ensemble member, Dance Prairie Circuit). As an Expressive Art Practitioner (MA, EXA-CT, European Graduate School, 2019), she uses a multi-disciplinary approach to facilitate therapeutic Community Art programming—how can art build social healing and cohesion? She is the Justice Artistic Director at Robertson-Wesley United Church through the Spirited Arts Program, a secular outreach initiative creating opportunities to build community around Social Justice topics such as burnout, gender-based violence, Queer politics, conflict theories, and reconciliation.

She consults cultural centres and festivals (Edmonton Poetry Festival, Citadel Theatre, CKUA, Edmonton International Fringe Theatre Festival, SkirtsAFire) on accessibility measures to make performances for all and art as the public good. In 2024, she is a fellow at Akademie Schloss Solitude creating an Arts-based research performance on disabled contemporary dance and audio description (creating equitable meaning), and the artist's relationship to income.

Brooke also works as a Research Chair for Workplace Inclusion and Accessibility at NorQuest College (Edmonton/Canada). Her research and consultancy focuses the realms of Canadian audience accessibility, post–secondary, disability and employment.

Brooke Leifso's residency is part of the exchange programme with Akademie Schloss Solitude.